Friday, July 13, 2007

Gir From Invader Zim Bra

Hepatitis C

The infectious agent, the virus (HCV Hepacavirus) is part of the family Flaviviridae. We identified six different genotypes and more than 90 sub-types. It is not yet clear whether there are differences in the clinical course of disease for different genotypes, but there are differences in the response of various genotypes to antiviral therapies.
acute HCV infection is very often asintomatica ed anitterica (in oltre i 2/3 dei casi ).

SINTOMI: I sintomi, quando presenti, sono caratterizzati da dolori muscolari, nausea , vomito, febbre, dolori addominali ed ittero. Un decorso fulminante fatale si osserva assai raramente (0,1%). L’infezione acuta diventa cronica in una elevatissima percentuale dei casi, stimata fino all’85%. Il 20-30 % dei pazienti con Epatite cronica C sviluppa nell’arco di 10-20 anni una cirrosi e l’epatocarcinoma può evolvere da una persistente cirrosi da HCV in circa l’1-4% dei pazienti per anno.

La distribuzione del virus è universale. L’infezione affects about 3% of world population. Individuals infected with HCV are 3.5000000 to 5,000,000 and about 4 million in the U.S.. In our country the proportion of infected individuals ranging from 3 to 12% of the general population with a gradient that grows in a north-south and with age. A particularly high frequency of infection was found in some African countries such as Cameroon and Egypt. The incubation period ranges from 2 weeks to 6 months, but for the most varied within 6-9 weeks.

HOW TO SEND: transmission occurs primarily via the parenteral apparent and not apparent. Are also been documented cases of infection through sexual contact, but this route seems to be much less efficient than for HBV. The infection can be transmitted vertically from mother to child via in less than 5% of cases. The control of blood donations, using the test for the detection of antibodies to HCV, has significantly reduced the risk of infection after blood transfusion and blood products.

PREVENTION: To date there is no vaccine for the 'Hepatitis C use of non-immunoglobulin was effective. The only really effective measures are represented by the observance of general hygiene the sterilization of instruments used for surgery and beauty treatments, the use of disposable materials and protection of high-risk sexual.

CARE Treatment of hepatitis C has improved considerably over the last ten years. Unlike any other chronic viral infection, a significant proportion of patients with chronic hepatitis C can be treated. However, the current standard of care - pegylated interferon alfa and ribavirin - has its limits. The limited effectiveness in patients with hepatitis C virus (HCV) genotype 1 and the side effect profile, require the development of new therapeutic approaches. New directions in treatment beyond interferon alpha-based therapies are on the horizon.

News probable treatment of hepatitis C


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